Facebook PixelA growing list of top biotech startup ideas
Brainstorming
Brainstorming
Brainstorming session

A growing list of top biotech startup ideas

A growing list of top biotech startup ideas

Image credit: Faria Anzum / unsplash.com

By Darko Savic on Aug 19, 2020

Creative contributions

Microbial strain bank for antibiotic producing microbes

[1] Dhakar, K., & Pandey, A. (2020). Microbial Ecology from the Himalayan Cryosphere Perspective. Microorganisms, 8(2), 257. https://doi.org/10.3390/microorganisms8020257

[2] Sapkota, A., Thapa, A., Budhathoki, A., Sainju, M., Shrestha, P., & Aryal, S. (2020). Isolation, Characterization, and Screening of Antimicrobial-Producing Actinomycetes from Soil Samples. International journal of microbiology, 2020, 2716584. https://doi.org/10.1155/2020/2716584

by Subash Chapagain on Sep 02, 2020

Gene therapy to induce tooth re-growth

[1] Takahashi, K., Kiso, H., Murashima-Suginami, A. et al. Development of tooth regenerative medicine strategies by controlling the number of teeth using targeted molecular therapy. Inflamm Regener 40, 21 (2020). https://doi.org/10.1186/s41232-020-00130-x

by Darko Savic on Oct 05, 2020

Remodeling adipose tissue to achieve weight loss

[1] Kuryłowicz, Alina, and Monika Puzianowska-Kuźnicka. “Induction of Adipose Tissue Browning as a Strategy to Combat Obesity.” International journal of molecular sciences vol. 21,17 6241. 28 Aug. 2020, doi:10.3390/ijms21176241

by Manel Lladó Santaeularia on Nov 23, 2020

Shubhankar Kulkarni 6 days ago
The treatment may need to be genetic since you want to "teach" the WAT to burn fat or teach the BAT to burn more fat. Also, burning more fat may lead to heat accumulation that may or may not have an outlet. I don't know whether simply burning fat without it being accompanied by physical exertion and the increase in the heart rate can stimulate sweating. Also, since liposuction has greatly advanced and is now minimally invasive, do we need to go through the pain of modifying the DNA (with all its side-effects) to have a similar effect?

Mass culturing the most potent nematodes for pest control

[1] Kaya H.K., Gaugler R. 1993. Entomopathogenic nematodes. Annual Review of Entomology, 38: 181–206.

[2] Boemare N.E., Laumond C., Mauleon H. 1996. The entomopathogenic nematode-bacterium complex: biology, life cycle and vertebrate safety. Biocontrol Science Technology, 6: 333–346.

[3] Griffin C.T., Downes M.J., Block W. 1990. Test of Antarctic soils for insect parasitic nematodes. Antarctic Science, 2: 221–222.

by Subash Chapagain on Nov 25, 2020

Cure for allergies by eliminating the memory cells that produce the antibodies

by Darko Savic on Aug 19, 2020

Gene therapies to remove latent viruses

by Darko Savic on Aug 19, 2020

Cell Cleansing Therapy

by Jamila on Aug 20, 2020

Darko Savic 3 months ago
I would sign up for such therapy on a yearly basis:)
Jamila 3 months ago
I would too! It would be amazing!

Self-replicating biodegradable utensils (growing spoons)

by Dragan Otasevic on Aug 21, 2020

Mouth microbiota modification therapy to protect your teeth better than tooth paste

by Darko Savic on Aug 21, 2020

Fully automated and autonomous mouse lab

by Dragan Otasevic on Aug 22, 2020

Finding a way to induce suspended animation in humans

by Jamila on Aug 24, 2020

Shubhankar Kulkarni 3 months ago
This will be useful for trips into space!
Darko Savic 3 months ago
I'm trying to imagine a company offering this as a service. Who would their end customers be? Some things that come to mind: long-duration travel (trips that take more than several hours), people who are terminally ill or in serious pain while waiting for the cure which is still some time away, people in prison - although suitable candidates would probably not be eligible:)
Jamila 3 months ago
Oh yes! It could benefit various people. It would be great for long-distance travel like in space!

MedicSmartPhones as Next generation Point of care testing Devices

by Arvind kumar sharma on Aug 27, 2020

Darko Savic 3 months ago
In other words, StarTrek tricorder?:) https://en.wikipedia.org/wiki/Tricorder

One protocol to rule them all

by christos stefanis on Aug 29, 2020

Shubhankar Kulkarni a month ago
Great idea! Even different labs perform different assays differently. They use different reagents, and they claim that their results might have something to do with the reagents they used and the protocols they followed. So, here is an idea (https://brainstorming.com/ideas/order-lab-reagents-using-study-protocols/47) for an online repository that lists the different reagents (their make and batch) a particular lab has used for the experiments. They also attach their protocols for others to reproduce the results.

Plant tissue culture kits for growing medicinal, nutraceutical, and endangered plants at home

by Felix Krengel on Aug 29, 2020

Apply Bacteria to the Scalp for Hair Regeneration

by Jamila on Aug 31, 2020

Darko Savic 3 months ago
Also, engineer one of the bacterial species usually found in the scalp microbiota to secrete something beneficial to the scalp.

Sugar Plastic

by Daniel - on Sep 02, 2020

Darko Savic 3 months ago
This is definitely an area worth pursuing. Some big players have entered this market already. For example DuPont with their polyester-based polymer called Poly-Trimethylene Terephthalate (or PTT, under the commercial name SORONA). For a new startup entering the field the parameters to try to improve are: cost, properties, and degradability.

Upcycle organic waste into food supplements

by Loukik Arora on Sep 12, 2020

A DIY phytochemical (essential oil) extraction kit

by Subash Chapagain on Sep 19, 2020

Designer microbiome

by Darko Savic on Sep 21, 2020

Darko Savic 2 months ago
This came up:) https://www.npr.org/templates/story/story.php?storyId=90014997&t=1600706282780

A database of super-genes and plasmid delivery service

by Darko Savic on Oct 15, 2020

Company that stores your data in the DNA

by Shubhankar Kulkarni on Nov 02, 2020

Supplying foods with specific bacteria (probiotics)

by Shubhankar Kulkarni on Nov 23, 2020

Darko Savic 7 days ago
David Sinclair spoke highly of Bravo probiotic yogurt. It contains 30ish species if I remember correctly. You get them in powder form and create your own yogurt at home. I made several batches. It tastes ok. Other than that, I have no noticeable results to report from it.

There was something that did bother me in the manufacturer's instructions. They said to mix it with honey. But honey kills all live bacteria on contact (https://www.youtube.com/watch?v=7FlzHiURdTs). It's an easy experiment to try. Any good enough microscope will do. I was surprised the yogurt manufacturer didn't know or failed to account for that.
Shubhankar Kulkarni 7 days ago
Darko Savic Right. I am also a bit repulsive towards consuming bacterial species that come in the form of powders. The bacterial viability is greatly hampered (https://www.sciencedirect.com/science/article/pii/S0023643816301566). The use of different preservatives further affects viability. The reference cited in the previous sentence shows that the viability can be maintained with microencapsulation using Ca-alginate biopolymer. But I think it may further increase the cost of the powder.

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Darko Savic 3 months ago
A good video describing the process for finding and validating biotech startup ideas - https://youtu.be/kmPJzABPwT4