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Designer armpit microbiome

Image credit: Billie via unsplash.com

Darko Savic
Darko Savic Nov 30, 2020




[4]Medline Plus (2012). "Hidradenitis suppurativa". U.S. National Library of Medicine. Archived from the original on 16 September 2012. Retrieved 19 September 2012.

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General comments

Jamila 3 months ago
Great idea.

There should be a comprehensive list/website that tells you which factors contribute to a "normal" smell and "bad" smells. For example, if a particular food is a significant driver of bad smell. Then people could use this information to change their dietary habits and see if that helps.

As people have already mentioned, various factors can affect the microbiome. So, the armpit microbiome transplant might not work continuously. However, for some people, even having temporary relief is better than smelling bad all the time. So, they might be up for regular armpit microbiome transplants.

In my opinion, it would be interesting to see how long a transplanted microbiome actually lasts!

Shubhankar Kulkarni
Shubhankar Kulkarni3 months ago
Jamila Right. The cost of the treatment along with the required frequency should be lesser than that of the prebiotic deodorant. Although we can identify foods that lead to sweat odor (like garlic, onion, meat, etc.), eliminating it from the diet can not be an option for many. However, as you pointed out, the temporary elimination of such foods does have significant effects on the odor. So, I think replacing the armpit microbiome may not be a permanent solution and may require regular sessions.
Shubhankar Kulkarni
Shubhankar Kulkarni3 months ago
A prebiotic (nutrients that foster the growth of good bacteria that are already part of your body) can be useful here. Not all bacteria and killing all bacteria on the skin may do more harm than good. Prebiotic components like xylitol help support the good bacteria and remove the bad. A prebiotic deodorant is also available that can maintain a healthy microbial composition on the skin.
Reference: https://www.tomsofmaine.com/good-matters/natural-products/all-about-armpit-bacteria-and-using-prebiotics-und#:~:text=It%20might%20seem%20unpleasant%20to,bacteria%20living%20in%20your%20armpits.&text=Specific%20armpit%20bacteria%2C%20like%20Corynebacteria,the%20FEMS%20Microbiology%20Ecology%20study.
Nitish3 months ago
Our microflora is basically of two types; transient and resident. The axilla (armpits), skin, nose, mouth, throat, large intestine, vagina, and hair follicles etc contains the myriad types of resident microbes. These microbes are generally well adapted for controlling such environments. They compete with transient microbes especially pathogens for food and shelter and eventually restrict the invading microbes from colonising their environ. So if we want to change the microbiome of the axilla or other parts, we firstly need to adapt the engineered/ donated microbes according to the host resident microflora. And, this we will have to do repeatedly to avoid any backshift in microbial composition. In addition to this, there are many other restrictions are also. Therefore, more or less this idea seems to be promising but also time-consuming with low probabilities of the permanent solution.
Povilas S
Povilas S3 months ago
The idea is really good, just the process of "inoculation" doesn't seem very appealing:D Also, does seeding a new bacterial microbiome guarantees you won't catch other types of bacteria on top of that? I suppose there are deeper reasons why some people have a better-smelling microbiome than others - it might be because of their diet, genetics, metabolism, etc. So the new microbiome may not be a fit for that person even if you tried to implant it there. And worse smell producing bacteria might be just the fit, so they'd find their way there sooner or later.