How could we scan DNA for mutations in real-time in vivo?
Image credit: https://unsplash.com/photos/iBnPWaIGXOE
Please leave the feedback on this challenge
Necessity
Is the problem still unsolved?
Conciseness
Is it concisely described?
Bounty for the best solution
Provide a bounty for the best solution
Bounties attract serious brainpower to the challenge.
[1]https://www.genome.gov/genetics-glossary/Mutation#:~:text=Definition,mutagens%20or%20a%20viral%20infection.
Creative contributions
A nanosensing mechanism that stays in the body and scans for mutation related activities
Please leave the feedback on this idea
Scanning live cells for the occurring mutations using Live-sec
[1]Guillaume-Gentil O, Grindberg RV, Kooger R, Dorwling-Carter L, Martinez V, Ossola D, Pilhofer M, Zambelli T, Vorholt JA. Tunable Single-Cell Extraction for Molecular Analyses. Cell. 2016 Jul 14;166(2):506-516. doi: 10.1016/j.cell.2016.06.025. PMID: 27419874.
[2]Chen, W., Guillaume-Gentil, O., Rainer, P.Y. et al. Live-seq enables temporal transcriptomic recording of single cells. Nature 608, 733–740 (2022). https://doi.org/10.1038/s41586-022-05046-9
Please leave the feedback on this idea
Please leave the feedback on this idea