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Removal of excess insulin via dialysis

Image credit: https://medcitynews.com/2011/02/home-dialysis-machine-market-heats-up-with-fresenius-entry/

Shubhankar Kulkarni
Shubhankar Kulkarni Aug 07, 2020

[1]Amico JA, Klein I : Diabetic management in patients with renal failure. Diabetes Care 1981; 4: 430–434

[2]Watve M. Doves, diplomats and diabetes: a Darwinian interpretation of type 2 diabetes and related disorders. New York: Springer, 2013

[3]Corkey B. Banting Lecture 2011: Hyperinsulinemia: Cause or Consequence? Diabetes. 2011;61:4–13. doi: 10.2337/db11-1483.

[4]Insulin Resistance and Hyperinsulinemia Is hyperinsulinemia the cart or the horse? Michael H. Shanik, Yuping Xu, Jan Škrha, Rachel Dankner, Yehiel Zick, and Jesse Roth. Diabetes Care 2008 Feb; 31(Supplement 2): S262-S268. https://doi.org/10.2337/dc08-s264

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General comments

Darko Savic
Darko Savic6 months ago
How could this kind of solution be made practical, given that insulin spikes multiple times per day (after meals)?
Shubhankar Kulkarni
Shubhankar Kulkarni6 months ago
In diabetics, the baseline (fasting) insulin levels are higher than normal. Dialysis may be helpful in bringing down these baseline levels. Frequency of dialysis can be kept similar to that of patients with renal dysfunction.