A novel endometriosis blood test
Image credit: National Cancer Institute
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- Pelvic pain
- Feeling tired
- Heavy bleeding
- Problems with conceiving
- CA-125 - ⬆️ High CA-125 levels were reported in endometriosis patients.
- BDNF - ⬆️ High BDNF levels in endometriosis patients. Plasma BDNF levels correlate with pain severity.
- MicroRNA - ⬆️ 4 microRNA levels were increased: miR-125b-5p, miR-150-5p, miR-342-3p, and miR-451a. ⬇️ 2 microRNA levels were reduced: miR-3613-5p and let-7b in endometriosis patients.
- Leptin - ⬆️ High Leptin levels in endometriosis patients compared with controls. Furthermore, Leptin levels increased with clinical staging. Therefore, Leptin can be used to determine the severity of endometriosis.
Karimi-Zarchi, Mojgan, et al. "Correlation of CA-125 serum level and clinico-pathological characteristic of patients with endometriosis." International Journal of Reproductive BioMedicine 14.11 (2016): 713.
Perricos, Alexandra, et al. "Increased serum levels of mBDNF in women with minimal and mild endometriosis have no predictive power for the disease." Experimental Biology and Medicine 243.1 (2018): 50-56.
Moustafa, Sarah, et al. "Accurate diagnosis of endometriosis using serum microRNAs." American journal of obstetrics and gynecology 223.4 (2020): 557-e1.
Hussein, Shatha Sami, Fatin Shallal Farhan, and Alaa Ibrahim Ali. "Serum Leptin as a Marker for Severity of Endometriosis." Obstetrics and Gynecology International 2020 (2020).