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What are the hurdles and drawbacks of Telomerase reactivation?

Image credit: http://www.askdrray.com/telomere-length-a-telltale-sign-of-aging/

Nitish Feb 04, 2021

[1]Jiang, H., Ju, Z. and Rudolph, K.L., 2007. Telomere shortening and ageing. Zeitschrift für Gerontologie und Geriatrie, 40(5), pp.314-324.

[2]Zhang, X., Mar, V., Zhou, W., Harrington, L. and Robinson, M.O., 1999. Telomere shortening and apoptosis in telomerase-inhibited human tumor cells. Genes & development, 13(18), pp.2388-2399.

[3]Cong, Y.S., Wright, W.E. and Shay, J.W., 2002. Human telomerase and its regulation. Microbiology and molecular biology reviews, 66(3), pp.407-425.

[4]Mendelsohn, A.R. and Larrick, J.W., 2012. Ectopic expression of telomerase safely increases health span and life span. Rejuvenation research, 15(4), pp.435-438.

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