With respect to longevity, is it better to "go hungry" or "go running"?
Image credit: https://www.pexels.com/photo/vegetable-salad-on-white-ceramic-plate-1211887/; https://www.pexels.com/photo/active-adult-athlete-body-416778/
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Is caloric restriction better than burning the calories?
- when fed equally, rats who exercised, on average, lived longer than those who didn't
- the max lifespan of exercising rats was not higher than the max lifespan of non-exercising ones
- rats that eat normally and exercise live shorter than rats that eat less and do not exercise
- mice that eat more have higher insulin levels, even if they exercise
- mice that eat a lot have the highest IGF-1 levels, compared to the ones eating less having the lowest
- caloric restriction changes levels of hormones in the body
- mice become healthier only if they start caloric restriction earlier
- restricting diet without fasting increases the lifespan of 20+ species
- exercise can help prevent diseases, which allows you to live your "normal" lifespan
- although it helps with diseases, exercise does not prolong the "expected" lifespan
- caloric restriction, without fasting, has a similar effect on diseases like exercise but also prolongs the lifespan if started early
American Physiological Society. "When It Comes To Living Longer, It's Better To Go Hungry Than Go Running, Mouse Study Suggests." ScienceDaily. ScienceDaily, 15 May 2008. <www.sciencedaily.com/releases/2008/05/080514064921.htm>
Oliver Hahn, Lisa F. Drews, An Nguyen, Takashi Tatsuta, Lisonia Gkioni, Oliver Hendrich, Qifeng Zhang, Thomas Langer, Scott Pletcher, Michael J. O. Wakelam, Andreas Beyer, Sebastian Grönke, Linda Partridge. A nutritional memory effect counteracts the benefits of dietary restriction in old mice. Nature Metabolism, 2019; DOI: 10.1038/s42255-019-0121-0
Justin Minnerly, Jiuli Zhang, Thomas Parker, Tiffany Kaul, Kailiang Jia. The cell non-autonomous function of ATG-18 is essential for neuroendocrine regulation of Caenorhabditis elegans lifespan. PLOS Genetics, 2017; 13 (5): e1006764 DOI: 10.1371/journal.pgen.1006764
Has anyone tried a combination of calorie restriction and exercise?
- No exercise + calorie restriction
- Exercise + normal diet
- Exercise + calorie restriction
- No exercise + normal diet
Please leave the feedback on this idea
Optimal use of both exercises and caloric restriction
Mobbs CV, Hof PR (eds): Body Composition and Aging. Interdiscipl Top Gerontol. Basel, Karger, 2010, vol 37, pp 157–174. doi: 10.1159/000320000