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Implantable living sensor paired with an external reader that digitizes the data

Darko Savic
Darko Savic Aug 27, 2021
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There are 2 aspects to this idea:

  1. An implantable, biochemical, living sensor that monitors the desired biomarkers (hormone levels, glucose, whatever) paired with a wearable device that detects changes in the sensor and digitizes the data in real-time.
  2. The sensor is made of the patient's own cells that have been reprogrammed to pluripotency and then developed into a gland-like mini-organ. This organ contains genetically modified cells that react to biomarker concentrations.

  • no foreign material in the body that the immune system could react to
  • the implanted "sensor" is powered by the food you eat
  • access to real-time, reliable data about the state of your health

Biochemistry and genetic engineering are outside of my area of expertise. Consider this science fiction until someone knowledgeable comes along with a more realistic perspective:)

I imagine taking a suitable cell (maybe from a gland) and reprogramming it back to pluripotent state or at least as far back as it needs to be taken to then want to develop into a mini organ. The resulting lump of cells would be programmed to react to increase/decrease of the target biomarkers.

The reaction would have to be detectable from the outside of the skin (reading device). So what reactions can be detected from the outside? A few options that come to mind:
  • bioluminescence
  • melanogenesis (can melatonin be reuptaken/degraded fast enough?)
  • inflamation
  • pulsating movement (muscle twitching)
  • bioelectrogenesis (Electric eel style, only smaller scale)
  • what else?
The sensor cells would react differently to different biomarkers. That way they could be multipurpose.

The mini-organ would be grown in vitro, around an artificial blood vessel. Upon implantation, the entire lump, as well as the vessel, would be attached to a blood vessel at a suitable location under the skin. Maybe on the wrist or on a finger. An Oura type ring could be used to detect the changes in the sensor organ.

Creative contributions

Injectable living sensors

Darko Savic
Darko Savic Aug 27, 2021
In the distant future a "sensor cell" could be injected under the skin. Like a benign tumor, it would then develop on its own into the final form - a mini-organ that reacts to stuff it detects.
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