Image credit: Chu et al. 2019 (https://www.nature.com/articles/s41467-019-09402-8)
Jamila Dec 01, 2020
Could we develop a hair regeneration hat for humans?
The idea is to create a hat that will use mechanical force to stimulate hair growth on the scalp.
A study has mentioned using a device that stretches the skin to grow hair. In the study, the researchers found that using mechanical stimulation for a week allowed hair regeneration in mice. They found that this method recruited hair stem cells and increased IGF-1 (insulin-like growth factor-1) and HGF (hepatocyte growth factor) secretion by the macrophages. Furthermore, the WNT pathway that has been associated with hair regeneration previously was highly active when the stretching device was used.
The research study was conducted on young mice. Would we get the same results for older mice?
Would prolonged mechanical stimulation on the human scalp induce hair regeneration?
How much pressure would be required to stimulate hair growth in humans? Would the amount of pressure be tolerable/safe?
What do you think of the idea?
Chu, Szu-Ying, et al. "Mechanical stretch induces hair regeneration through the alternative activation of macrophages." Nature communications 10.1 (2019): 1-11.