Can microbes in the blood and tissues help to detect cancer?
Image credit: https://www.medicalnewstoday.com/articles/321000
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- If it is so revolutionary, how come there is only one paper and company working on it (no other literature proofs except the Micronoma team)?
- Are the microbial components in blood a consequence or a cause of the disease?
- Does finding specific microbial populations in the blood mean that these microbes live in the disease/cancer tissue?
S. bovis/ gallolyticus is found in blood of colon cancer patients
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Vaska VL, Faoagali JL. Streptococcus bovis bacteraemia: identification within organism complex and association with endocarditis and colonic malignancy. Pathology. 2009 Feb;41(2):183-6. doi: 10.1080/00313020802436816. PMID: 18972318.
Tripodi MF, Adinolfi LE, Ragone E, Durante Mangoni E, Fortunato R, Iarussi D, Ruggiero G, Utili R. Streptococcus bovis endocarditis and its association with chronic liver disease: an underestimated risk factor. Clin Infect Dis. 2004 May 15;38(10):1394-400. doi: 10.1086/392503. Epub 2004 Apr 28. PMID: 15156477.
Zarkin BA, Lillemoe KD, Cameron JL, Effron PN, Magnuson TH, Pitt HA. The triad of Streptococcus bovis bacteremia, colonic pathology, and liver disease. Ann Surg. 1990 Jun;211(6):786-91; discussion 791-2. doi: 10.1097/00000658-199006000-00019. PMID: 2357141; PMCID: PMC1358139.